Cargando…

A novel machine learning-based approach for the computational functional assessment of pharmacogenomic variants

BACKGROUND: The field of pharmacogenomics focuses on the way a person’s genome affects his or her response to a certain dose of a specified medication. The main aim is to utilize this information to guide and personalize the treatment in a way that maximizes the clinical benefits and minimizes the r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pandi, Maria-Theodora, Koromina, Maria, Tsafaridis, Iordanis, Patsilinakos, Sotirios, Christoforou, Evangelos, van der Spek, Peter J., Patrinos, George P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351412/ https://www.ncbi.nlm.nih.gov/pubmed/34372920 http://dx.doi.org/10.1186/s40246-021-00352-1

Ejemplares similares

Exome-Wide Analysis of the DiscovEHR Cohort Reveals Novel Candidate Pharmacogenomic Variants for Clinical Pharmacogenomics
por: Pandi, Maria-Theodora, et al.
Publicado: (2020)

Delineating significant genome-wide associations of variants with antipsychotic and antidepressant treatment response: implications for clinical pharmacogenomics
por: Koromina, Maria, et al.
Publicado: (2020)

A Novel Text-Mining Approach for Retrieving Pharmacogenomics Associations From the Literature
por: Pandi, Maria-Theodora, et al.
Publicado: (2020)

Development of the pharmacogenomics and genomics literacy framework for pharmacists
por: Rahma, Azhar T., et al.
Publicado: (2021)

Whole genome sequencing in pharmacogenomics
por: Katsila, Theodora, et al.
Publicado: (2015)

Examining key factors impact on health science students’ intentions to adopt genetic and pharmacogenomics testing: a comparative path analysis in two different healthcare settings
por: Koufaki, Margarita-Ioanna, et al.
Publicado: (2022)

Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients
por: Chondrou, Vasiliki, et al.
Publicado: (2017)

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach
por: Karageorgos, Ioannis, et al.
Publicado: (2015)

Exploring public genomics data for population pharmacogenomics
por: Lakiotaki, Kleanthi, et al.
Publicado: (2017)

Pharmacovariome scanning using whole pharmacogene resequencing coupled with deep computational analysis and machine learning for clinical pharmacogenomics
por: Tafazoli, Alireza, et al.
Publicado: (2023)

Pharmacometabolomics-aided Pharmacogenomics in Autoimmune Disease
por: Katsila, Theodora, et al.
Publicado: (2016)

Integrating Next-Generation Sequencing in the Clinical Pharmacogenomics Workflow
por: Giannopoulou, Efstathia, et al.
Publicado: (2019)

ACE2-based capacitance sensor for rapid native SARS-CoV-2 detection in biological fluids and its correlation with real-time PCR
por: Georgas, A., et al.
Publicado: (2022)

ePGA: A Web-Based Information System for Translational Pharmacogenomics
por: Lakiotaki, Kleanthi, et al.
Publicado: (2016)

Editorial: Pharmacogenomics and ethnicity: Prevalence and clinical significance of pharmacogenomic biomarkers in indigenous and other populations
por: Patrinos, George P., et al.
Publicado: (2023)

Novel genetic risk variants for pediatric celiac disease
por: Balasopoulou, Angeliki, et al.
Publicado: (2016)

General considerations for integrating pharmacogenomics into mainstream medical practice
por: Patrinos, George P
Publicado: (2010)

Deciphering next-generation pharmacogenomics: an information technology perspective
por: Potamias, George, et al.
Publicado: (2014)

Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine
por: Mahmutovic, Lejla, et al.
Publicado: (2018)

Perception of personalized medicine, pharmacogenomics, and genetic testing among undergraduates in Hong Kong
por: Cheung, Nicholas Yan Chai, et al.
Publicado: (2021)

6th Golden Helix Pharmacogenomics Day: pharmacogenomics and individualized therapy
por: Stojiljkovic, Maja, et al.
Publicado: (2012)

Comparative study and meta-analysis of meta-analysis studies for the correlation of genomic markers with early cancer detection
por: Lanara, Zoi, et al.
Publicado: (2013)

Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients
por: Mitropoulos, Konstantinos, et al.
Publicado: (2017)

Prevalence of pharmacogenomic variants in 100 pharmacogenes among Southeast Asian populations under the collaboration of the Southeast Asian Pharmacogenomics Research Network (SEAPharm)
por: Runcharoen, Chakkaphan, et al.
Publicado: (2021)

Leveraging the utility of pharmacogenomics in psychiatry through clinical decision support: a focus group study
por: Goodspeed, Andrew, et al.
Publicado: (2019)

Dose Optimization in Oncology Drug Development: The Emerging Role of Pharmacogenomics, Pharmacokinetics, and Pharmacodynamics
por: Papachristos, Apostolos, et al.
Publicado: (2023)

Toxicity and Pharmacogenomic Biomarkers in Breast Cancer Chemotherapy
por: Al-Mahayri, Zeina N., et al.
Publicado: (2020)

Systematic review of economic evaluation studies in psychiatric pharmacogenomics
por: Mitropoulou, C., et al.
Publicado: (2021)

Editorial: Brief research reports in pharmacogenetics and pharmacogenomics: 2022
por: Sessa, Francesco, et al.
Publicado: (2023)

A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics
por: Mizzi, Clint, et al.
Publicado: (2016)

Association of genome variations in the renin-angiotensin system with physical performance
por: Sgourou, Argyro, et al.
Publicado: (2012)

Editorial: Integration of computational genomics into clinical pharmacogenomic tests: how bioinformatics may help primary care in precision medicine area
por: Tafazoli, Alireza, et al.
Publicado: (2023)

Discovery of new drug indications for COVID-19: A drug repurposing approach
por: Kumari, Priyanka, et al.
Publicado: (2022)

Machine Learning and Deep Learning for the Pharmacogenomics of Antidepressant Treatments
por: Lin, Eugene, et al.
Publicado: (2021)

Medical education in pharmacogenomics—results from a survey on pharmacogenetic knowledge in healthcare professionals within the European pharmacogenomics clinical implementation project Ubiquitous Pharmacogenomics (U-PGx)
por: Just, Katja Susanne, et al.
Publicado: (2017)

Correction: A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics
por: Mizzi, Clint, et al.
Publicado: (2017)

Adoption of Pharmacogenomic Testing: A Marketing Perspective
por: Koufaki, Margarita-Ioanna, et al.
Publicado: (2021)

HDAC3 role in medication consumption in medication overuse headache patients: a pilot study
por: Pisanu, Claudia, et al.
Publicado: (2015)

Editorial: The Potential of Machine Learning in Pharmacogenetics, Pharmacogenomics and Pharmacoepidemiology
por: Garcia-Agundez, Augusto, et al.
Publicado: (2022)

Genome-based therapeutic interventions for β-type hemoglobinopathies
por: Karamperis, Kariofyllis, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9rjponbnfpf6vofmbm5l47812a