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Indomethacin Treatment Post-irradiation Improves Mouse Parotid Salivary Gland Function via Modulation of Prostaglandin E(2) Signaling

Annually, >600,000 new cases of head and neck cancer (HNC) are diagnosed worldwide with primary treatment being surgery and radiotherapy. During ionizing radiation (IR) treatment of HNC, healthy salivary glands are collaterally damaged, leading to loss of function that severely diminishes the qua...

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Detalles Bibliográficos
Autores principales: Gilman, Kristy E., Camden, Jean M., Woods, Lucas T., Weisman, Gary A., Limesand, Kirsten H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351468/
https://www.ncbi.nlm.nih.gov/pubmed/34381764
http://dx.doi.org/10.3389/fbioe.2021.697671