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Glycosylation of recombinant rabbit immunoglobulins influences protease susceptibility as shown by comprehensive mass spectrometric glycan analysis

Recombinant immunoglobulins (rIgGs) have become increasingly important as therapeutic agents and diagnostic tools in recent years. Genetic engineering allows the introduction of non-natural features such as the Sortase motif for site-directed labeling. In this study, the enzyme Sortase A (SrtA) was...

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Detalles Bibliográficos
Autores principales:	Friligou, Irene, Gassner, Jana, Knoblauch, Dominic, Kagerer, Gabriele, Popp, Franziska, Voit, Susanne, Engel, Alfred M, Leinenbach, Andreas, Steffen, Wojtek, Haberger, Markus, Tabarés, Glòria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Analytical Glycobiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351503/ https://www.ncbi.nlm.nih.gov/pubmed/33554253 http://dx.doi.org/10.1093/glycob/cwab010

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