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Apolipoprotein C‐II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway

BACKGROUND: Peritoneal metastasis (PM) occurs frequently in patients with gastric cancer (GC) and confers poor survival. Lipid metabolism acts as a non‐negligible regulator in epithelial–mesenchymal transition (EMT), which is crucial for the metastasis of GC. As apolipoprotein C2 (APOC2) is a key ac...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Yang, Zhi, Xu, En, Shen, Xiaofei, Wang, Xingzhou, Li, Zijian, Yu, Heng, Chen, Kai, Hu, Qiongyuan, Xia, Xuefeng, Liu, Song, Guan, Wenxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351524/
https://www.ncbi.nlm.nih.gov/pubmed/34459127
http://dx.doi.org/10.1002/ctm2.522