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SET levels contribute to cohesion fatigue

Chromosome instability (CIN) is a major hallmark of cancer cells and believed to drive tumor progression. Several cellular defects including weak centromeric cohesion are proposed to promote CIN, but the molecular mechanisms underlying these defects are poorly understood. In a screening for SET prot...

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Detalles Bibliográficos
Autores principales: Yang, Lu, Zhang, Qian, Niu, Tianhua, Liu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351544/
https://www.ncbi.nlm.nih.gov/pubmed/33909454
http://dx.doi.org/10.1091/mbc.E20-12-0778