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Flexible pivoting of dynamin pleckstrin homology domain catalyzes fission: insights into molecular degrees of freedom

The neuronal dynamin1 functions in the release of synaptic vesicles by orchestrating the process of GTPase-dependent membrane fission. Dynamin1 associates with the plasma membrane–localized phosphatidylinositol-4,5-bisphosphate (PIP(2)) through the centrally located pleckstrin homology domain (PHD)....

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Detalles Bibliográficos
Autores principales: Baratam, Krishnakanth, Jha, Kirtika, Srivastava, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351549/
https://www.ncbi.nlm.nih.gov/pubmed/33979205
http://dx.doi.org/10.1091/mbc.E20-12-0794

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