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Flexible pivoting of dynamin pleckstrin homology domain catalyzes fission: insights into molecular degrees of freedom
The neuronal dynamin1 functions in the release of synaptic vesicles by orchestrating the process of GTPase-dependent membrane fission. Dynamin1 associates with the plasma membrane–localized phosphatidylinositol-4,5-bisphosphate (PIP(2)) through the centrally located pleckstrin homology domain (PHD)....
Autores principales: | Baratam, Krishnakanth, Jha, Kirtika, Srivastava, Anand |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351549/ https://www.ncbi.nlm.nih.gov/pubmed/33979205 http://dx.doi.org/10.1091/mbc.E20-12-0794 |
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