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Structural insights into the cause of human RSPH4A primary ciliary dyskinesia

Cilia and flagella are evolutionarily conserved eukaryotic organelles involved in cell motility and signaling. In humans, mutations in Radial Spoke Head Component 4A (RSPH4A) can lead to primary ciliary dyskinesia (PCD), a life-shortening disease characterized by chronic respiratory tract infections...

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Detalles Bibliográficos
Autores principales:	Zhao, Yanhe, Pinskey, Justine, Lin, Jianfeng, Yin, Weining, Sears, Patrick R., Daniels, Leigh A., Zariwala, Maimoona A., Knowles, Michael R., Ostrowski, Lawrence E., Nicastro, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351563/ https://www.ncbi.nlm.nih.gov/pubmed/33852348 http://dx.doi.org/10.1091/mbc.E20-12-0806

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