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Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions
Patients with metastatic castration-resistant prostate cancer (mCRPC) have an average survival of only 13 months. Identification of novel predictive and actionable biomarkers in the homologous recombination repair (HRR) pathway in up to a quarter of patients with mCRPC has led to the approval of tar...
Autores principales: | Scott, Rodney J., Mehta, Anurag, Macedo, Gabriel S., Borisov, Pavel S., Kanesvaran, Ravindran, El Metnawy, Wafaa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351605/ https://www.ncbi.nlm.nih.gov/pubmed/34381565 http://dx.doi.org/10.18632/oncotarget.28015 |
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