The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation

Fraxetin, a natural product isolated and purified from the bark of Fraxinus bungeana A.DC., has anti-inflammatory, analgesic, and anti-dysenteric activities. This study aimed to investigate the anti-tumor effects of fraxetin in pancreatic ductal adenocarcinoma (PDA). The effects of fraxetin on the m...

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Detalles Bibliográficos
Autores principales: Guo, Yangyang, Xiao, Yanyi, Guo, Hangcheng, Zhu, Hengyue, Chen, Dong, Wang, Jilong, Deng, Junjie, Lan, Junjie, Liu, Xiaodong, Zhang, Qiyu, Bai, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351699/
https://www.ncbi.nlm.nih.gov/pubmed/34320467
http://dx.doi.org/10.18632/aging.203301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351699/
https://www.ncbi.nlm.nih.gov/pubmed/34320467
http://dx.doi.org/10.18632/aging.203301

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