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The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation
Fraxetin, a natural product isolated and purified from the bark of Fraxinus bungeana A.DC., has anti-inflammatory, analgesic, and anti-dysenteric activities. This study aimed to investigate the anti-tumor effects of fraxetin in pancreatic ductal adenocarcinoma (PDA). The effects of fraxetin on the m...
Autores principales: | Guo, Yangyang, Xiao, Yanyi, Guo, Hangcheng, Zhu, Hengyue, Chen, Dong, Wang, Jilong, Deng, Junjie, Lan, Junjie, Liu, Xiaodong, Zhang, Qiyu, Bai, Yongheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351699/ https://www.ncbi.nlm.nih.gov/pubmed/34320467 http://dx.doi.org/10.18632/aging.203301 |
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