Improved antimalarial activity of caprol-based nanostructured lipid carriers encapsulating artemether-lumefantrine for oral administration

BACKGROUND: Artemether and lumefantrine display low aqueous solubility leading to poor release profile; hence the need for the use of lipid-based systems to improve their oral bioavailability so as to improve their therapeutic efficacy. AIM AND OBJECTIVE: The objective of this work was to utilize po...

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Detalles Bibliográficos
Autores principales: Akpa, Paul Achile, Ugwuoke, Joseph Abuchi, Attama, Anthony Amaechi, Ugwu, Chinenye Nnenna, Ezeibe, Ezinwanne Nneoma, Momoh, Mumuni Audu, Echezona, Adaeze Chidiebere, Kenechukwu, Franklin Chimaobi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351851/
https://www.ncbi.nlm.nih.gov/pubmed/34394228
http://dx.doi.org/10.4314/ahs.v20i4.20

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