Cargando…
Treatment With Suboptimal Dose of Benznidazole Mitigates Immune Response Molecular Pathways in Mice With Chronic Chagas Cardiomyopathy
Chronic Chagas cardiomyopathy (CCC) is the most frequent and severe form of Chagas disease, a neglected tropical illness caused by the protozoan Trypanosoma cruzi, and the main cause of morbimortality from cardiovascular problems in endemic areas. Although efforts have been made to understand the si...
Autores principales: | Farani, Priscila Silva Grijó, Begum, Khodeza, Vilar-Pereira, Glaucia, Pereira, Isabela Resende, Almeida, Igor C., Roy, Sourav, Lannes-Vieira, Joseli, Moreira, Otacilio Cruz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351877/ https://www.ncbi.nlm.nih.gov/pubmed/34381739 http://dx.doi.org/10.3389/fcimb.2021.692655 |
Ejemplares similares
-
Treatment with benznidazole and pentoxifylline regulates microRNA transcriptomic profile in a murine model of Chagas chronic cardiomyopathy
por: Silva Grijó Farani, Priscila, et al.
Publicado: (2023) -
Combination Chemotherapy with Suboptimal Doses of Benznidazole and Pentoxifylline Sustains Partial Reversion of Experimental Chagas' Heart Disease
por: Vilar-Pereira, Glaucia, et al.
Publicado: (2016) -
Memory impairment in chronic experimental Chagas disease: Benznidazole therapy reversed cognitive deficit in association with reduction of parasite load and oxidative stress in the nervous tissue
por: Vilar-Pereira, Glaucia, et al.
Publicado: (2021) -
Tumor Necrosis Factor Is a Therapeutic Target for Immunological Unbalance and Cardiac Abnormalities in Chronic Experimental Chagas' Heart Disease
por: Pereira, Isabela Resende, et al.
Publicado: (2014) -
Severity of chronic experimental Chagas' heart disease parallels tumour
necrosis factor and nitric oxide levels in the serum: models of mild and severe
disease
por: Pereira, Isabela Resende, et al.
Publicado: (2014)