Prognostic impact of corticosteroids on efficacy of chimeric antigen receptor T-cell therapy in large B-cell lymphoma

Corticosteroids are commonly used for the management of severe toxicities associated with chimeric antigen receptor (CAR) T-cell therapy. However, it remains unclear whether their dose, duration, and timing may affect clinical efficacy. Here, we determined the impact of corticosteroids on clinical o...

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Detalles Bibliográficos
Autores principales: Strati, Paolo, Ahmed, Sairah, Furqan, Fateeha, Fayad, Luis E., Lee, Hun J., Iyer, Swaminathan P., Nair, Ranjit, Nastoupil, Loretta J., Parmar, Simrit, Rodriguez, Maria A., Samaniego, Felipe, Steiner, Raphael E., Wang, Michael, Pinnix, Chelsea C., Horowitz, Sandra B., Feng, Lei, Sun, Ryan, Claussen, Catherine M., Hawkins, Misha C., Johnson, Nicole A., Singh, Prachee, Mistry, Haleigh, Johncy, Swapna, Adkins, Sherry, Kebriaei, Partow, Shpall, Elizabeth J., Green, Michael R., Flowers, Christopher R., Westin, Jason, Neelapu, Sattva S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Gene Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351896/
https://www.ncbi.nlm.nih.gov/pubmed/33534891
http://dx.doi.org/10.1182/blood.2020008865

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