Adenomatous Polyposis Coli loss controls cell cycle regulators and response to paclitaxel in MDA-MB-157 metaplastic breast cancer cells

Adenomatous Polyposis Coli (APC) is lost in approximately 70% of sporadic breast cancers, with an inclination towards triple negative breast cancer (TNBC). TNBC is treated with traditional chemotherapy, such as paclitaxel (PTX); however, tumors often develop drug resistance. We previously created AP...

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Detalles Bibliográficos
Autores principales: Astarita, Emily M., Maloney, Sara M., Hoover, Camden A., Berkeley, Bronwyn J., VanKlompenberg, Monica K., Nair, T. Murlidharan, Prosperi, Jenifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351968/
https://www.ncbi.nlm.nih.gov/pubmed/34370741
http://dx.doi.org/10.1371/journal.pone.0255738

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