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Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough?

The U.S. with only 4% of the world’s population, bears a disproportionate share of infections in the COVID-19 pandemic. To understand this puzzle, we investigate how mitigation strategies and compliance can work together (or in opposition) to reduce (or increase) the spread of COVID-19 infection. Bu...

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Detalles Bibliográficos
Autores principales: Mukerjee, Swati, Chow, Clifton M., Li, Mingfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351990/
https://www.ncbi.nlm.nih.gov/pubmed/34370739
http://dx.doi.org/10.1371/journal.pone.0239352
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author Mukerjee, Swati
Chow, Clifton M.
Li, Mingfei
author_facet Mukerjee, Swati
Chow, Clifton M.
Li, Mingfei
author_sort Mukerjee, Swati
collection PubMed
description The U.S. with only 4% of the world’s population, bears a disproportionate share of infections in the COVID-19 pandemic. To understand this puzzle, we investigate how mitigation strategies and compliance can work together (or in opposition) to reduce (or increase) the spread of COVID-19 infection. Building on the Oxford index, we create state-specific stringency indices tailored to U.S. conditions, to measure the degree of strictness of public mitigation measures. A modified time-varying SEIRD model, incorporating this Stringency Index as well as a Compliance Indicator is then estimated with daily data for a sample of 6 U.S. states: New York, New Hampshire, New Mexico, Colorado, Texas, and Arizona. We provide a simple visual policy tool to evaluate the various combinations of mitigation policies and compliance that can reduce the basic reproduction number to less than one, the acknowledged threshold in the epidemiological literature to control the pandemic. Understanding of this relationship by both the public and policy makers is key to controlling the pandemic. This tool has the potential to be used in a real-time, dynamic fashion for flexible policy options. Our methodology can be applied to other countries and has the potential to be extended to other epidemiological models as well. With this first step in attempting to quantify the factors that go into the “black box” of the transmission factor β, we hope that our work will stimulate further research in the dual role of mitigation policies and compliance.
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spelling pubmed-83519902021-08-10 Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough? Mukerjee, Swati Chow, Clifton M. Li, Mingfei PLoS One Research Article The U.S. with only 4% of the world’s population, bears a disproportionate share of infections in the COVID-19 pandemic. To understand this puzzle, we investigate how mitigation strategies and compliance can work together (or in opposition) to reduce (or increase) the spread of COVID-19 infection. Building on the Oxford index, we create state-specific stringency indices tailored to U.S. conditions, to measure the degree of strictness of public mitigation measures. A modified time-varying SEIRD model, incorporating this Stringency Index as well as a Compliance Indicator is then estimated with daily data for a sample of 6 U.S. states: New York, New Hampshire, New Mexico, Colorado, Texas, and Arizona. We provide a simple visual policy tool to evaluate the various combinations of mitigation policies and compliance that can reduce the basic reproduction number to less than one, the acknowledged threshold in the epidemiological literature to control the pandemic. Understanding of this relationship by both the public and policy makers is key to controlling the pandemic. This tool has the potential to be used in a real-time, dynamic fashion for flexible policy options. Our methodology can be applied to other countries and has the potential to be extended to other epidemiological models as well. With this first step in attempting to quantify the factors that go into the “black box” of the transmission factor β, we hope that our work will stimulate further research in the dual role of mitigation policies and compliance. Public Library of Science 2021-08-09 /pmc/articles/PMC8351990/ /pubmed/34370739 http://dx.doi.org/10.1371/journal.pone.0239352 Text en © 2021 Mukerjee et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Mukerjee, Swati
Chow, Clifton M.
Li, Mingfei
Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough?
title Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough?
title_full Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough?
title_fullStr Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough?
title_full_unstemmed Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough?
title_short Mitigation strategies and compliance in the COVID-19 fight; how much compliance is enough?
title_sort mitigation strategies and compliance in the covid-19 fight; how much compliance is enough?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8351990/
https://www.ncbi.nlm.nih.gov/pubmed/34370739
http://dx.doi.org/10.1371/journal.pone.0239352
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