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Prokineticin Receptor-1 Signaling Inhibits Dose- and Time-Dependent Anthracycline-Induced Cardiovascular Toxicity Via Myocardial and Vascular Protection

OBJECTIVES: This study investigated how different concentrations of doxorubicin (DOX) can affect the function of cardiac cells. This study also examined whether activation of prokineticin receptor (PKR)-1 by a nonpeptide agonist, IS20, prevents DOX-induced cardiovascular toxicity in mouse models. BA...

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Detalles Bibliográficos
Autores principales:	Gasser, Adeline, Chen, Yu-Wen, Audebrand, Anais, Daglayan, Ayhan, Charavin, Marine, Escoubet, Brigitte, Karpov, Pavel, Tetko, Igor, Chan, Michael W.Y., Cardinale, Daniela, Désaubry, Laurent, Nebigil, Canan G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352030/ https://www.ncbi.nlm.nih.gov/pubmed/34396166 http://dx.doi.org/10.1016/j.jaccao.2019.06.003

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