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The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study
AIMS: The aim of this study was to evaluate the remineralizing effect among various non-fluoridated toothpastes on artificial caries in primary teeth. MATERIALS AND METHODS: Fifty sound primary incisor teeth were embedded in self-curing acrylic resin and immersed in demineralizing solution for 4 day...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352058/ https://www.ncbi.nlm.nih.gov/pubmed/34430500 http://dx.doi.org/10.4103/jispcd.JISPCD_64_21 |
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author | Kasemkhun, Pornpailin Rirattanapong, Praphasri |
author_facet | Kasemkhun, Pornpailin Rirattanapong, Praphasri |
author_sort | Kasemkhun, Pornpailin |
collection | PubMed |
description | AIMS: The aim of this study was to evaluate the remineralizing effect among various non-fluoridated toothpastes on artificial caries in primary teeth. MATERIALS AND METHODS: Fifty sound primary incisor teeth were embedded in self-curing acrylic resin and immersed in demineralizing solution for 4 days forming artificial caries. All teeth were divided into five groups (10 teeth/group): Group I deionized water (control); Group II 1000 ppm F (Kodomo(®)); Group III non-fluoridated toothpaste containing calcium glycerophosphate and calcium lactate (Dokbuaku(®)); Group IV casein phosphopeptides-amorphous calcium phosphate (CPP-ACP) paste (GC Tooth Mousse(®)), and Group V non-fluoridated toothpaste containing nanohydroxyapatite (NHA) (Apagard(®)). The specimens were subjected to pH-cycling and immersed in toothpaste slurry twice for 7 days. Baseline, before, and after pH-cycling surface microhardness (SMH) values were measured by Vickers hardness numbers, and the percentage recovery of SMH (%SMHR) was calculated. Data were analyzed by one-way analysis of variance and Tukey’s multiple comparison at 95% confidence intervals. RESULTS: The SMH values of test groups were significantly higher than those of the control group (p = 0.00). The %SMHR was −5.72±7.03% in the control group, Group II was significantly higher than Group III but there were no significant differences among Groups II, IV, and V (p > 0.05). CONCLUSION: Non-fluoridated toothpastes containing CPP-ACP or NHA for young children had efficacy in remineralizing effect on primary teeth comparable with 1000 ppm fluoridated toothpaste. |
format | Online Article Text |
id | pubmed-8352058 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-83520582021-08-23 The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study Kasemkhun, Pornpailin Rirattanapong, Praphasri J Int Soc Prev Community Dent Original Article AIMS: The aim of this study was to evaluate the remineralizing effect among various non-fluoridated toothpastes on artificial caries in primary teeth. MATERIALS AND METHODS: Fifty sound primary incisor teeth were embedded in self-curing acrylic resin and immersed in demineralizing solution for 4 days forming artificial caries. All teeth were divided into five groups (10 teeth/group): Group I deionized water (control); Group II 1000 ppm F (Kodomo(®)); Group III non-fluoridated toothpaste containing calcium glycerophosphate and calcium lactate (Dokbuaku(®)); Group IV casein phosphopeptides-amorphous calcium phosphate (CPP-ACP) paste (GC Tooth Mousse(®)), and Group V non-fluoridated toothpaste containing nanohydroxyapatite (NHA) (Apagard(®)). The specimens were subjected to pH-cycling and immersed in toothpaste slurry twice for 7 days. Baseline, before, and after pH-cycling surface microhardness (SMH) values were measured by Vickers hardness numbers, and the percentage recovery of SMH (%SMHR) was calculated. Data were analyzed by one-way analysis of variance and Tukey’s multiple comparison at 95% confidence intervals. RESULTS: The SMH values of test groups were significantly higher than those of the control group (p = 0.00). The %SMHR was −5.72±7.03% in the control group, Group II was significantly higher than Group III but there were no significant differences among Groups II, IV, and V (p > 0.05). CONCLUSION: Non-fluoridated toothpastes containing CPP-ACP or NHA for young children had efficacy in remineralizing effect on primary teeth comparable with 1000 ppm fluoridated toothpaste. Wolters Kluwer - Medknow 2021-07-03 /pmc/articles/PMC8352058/ /pubmed/34430500 http://dx.doi.org/10.4103/jispcd.JISPCD_64_21 Text en Copyright: © 2021 Journal of International Society of Preventive and Community Dentistry https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Kasemkhun, Pornpailin Rirattanapong, Praphasri The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study |
title | The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study |
title_full | The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study |
title_fullStr | The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study |
title_full_unstemmed | The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study |
title_short | The Efficacy of Non-fluoridated Toothpastes on Artificial Enamel Caries in Primary Teeth: An In Vitro Study |
title_sort | efficacy of non-fluoridated toothpastes on artificial enamel caries in primary teeth: an in vitro study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352058/ https://www.ncbi.nlm.nih.gov/pubmed/34430500 http://dx.doi.org/10.4103/jispcd.JISPCD_64_21 |
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