Neutral Effects of Combined Treatment With GLP-1R Agonist Exenatide and MR Antagonist Potassium Canrenoate on Cardiac Function in Porcine and Murine Chronic Heart Failure Models

Background: Ischemia-reperfusion and cardiac remodeling is associated with cardiomyocyte death, excessive fibrosis formation, and functional decline, eventually resulting in heart failure (HF). Glucagon-like peptide (GLP)-1 agonists are reported to reduce apoptosis and myocardial infarct size after...

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Detalles Bibliográficos
Autores principales: Demkes, Evelyne J., Wenker, Steven, Silvis, Max J. M., van Nieuwburg, Martijn M. J., Visser, M. Joyce, Jansen, Marlijn S., Brans, Maike A. D., Velema, Evelyn, Sluijter, Joost P. G., Hoefer, Imo E., de Kleijn, Dominique P. V., Timmers, Leo, de Jager, Saskia C. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352472/
https://www.ncbi.nlm.nih.gov/pubmed/34381364
http://dx.doi.org/10.3389/fphar.2021.702326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352472/
https://www.ncbi.nlm.nih.gov/pubmed/34381364
http://dx.doi.org/10.3389/fphar.2021.702326

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