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MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detection
SUMMARY: DNA methylation patterns in a cell are associated with gene expression and the phenotype of a cell, including disease states. Bisulphite PCR sequencing is commonly used to assess the methylation profile of genomic regions between different cells. Here we have developed MethPanel, a computat...
Autores principales: | Luu, Phuc-Loi, Ong, Phuc-Thinh, Loc, Tran Thai Huu, Lam, Dilys, Pidsley, Ruth, Stirzaker, Clare, Clark, Susan J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352503/ https://www.ncbi.nlm.nih.gov/pubmed/33367555 http://dx.doi.org/10.1093/bioinformatics/btaa1060 |
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