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DNA Methylation of PGC-1α Is Associated With Elevated mtDNA Copy Number and Altered Urinary Metabolites in Autism Spectrum Disorder

Autism spectrum disorder (ASD) is a complex disorder that is underpinned by numerous dysregulated biological pathways, including pathways that affect mitochondrial function. Epigenetic mechanisms contribute to this dysregulation and DNA methylation is an important factor in the etiology of ASD. We m...

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Detalles Bibliográficos
Autores principales:	Bam, Sophia, Buchanan, Erin, Mahony, Caitlyn, O’Ryan, Colleen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352569/ https://www.ncbi.nlm.nih.gov/pubmed/34381777 http://dx.doi.org/10.3389/fcell.2021.696428

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