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Maternally inherited piRNAs direct transient heterochromatin formation at active transposons during early Drosophila embryogenesis

The PIWI-interacting RNA (piRNA) pathway controls transposon expression in animal germ cells, thereby ensuring genome stability over generations. In Drosophila, piRNAs are intergenerationally inherited through the maternal lineage, and this has demonstrated importance in the specification of piRNA s...

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Detalles Bibliográficos
Autores principales: Fabry, Martin H, Falconio, Federica A, Joud, Fadwa, Lythgoe, Emily K, Czech, Benjamin, Hannon, Gregory J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352587/
https://www.ncbi.nlm.nih.gov/pubmed/34236313
http://dx.doi.org/10.7554/eLife.68573