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VASP-mediated actin dynamics activate and recruit a filopodia myosin

Filopodia are thin, actin-based structures that cells use to interact with their environments. Filopodia initiation requires a suite of conserved proteins but the mechanism remains poorly understood. The actin polymerase VASP and a MyTH-FERM (MF) myosin, DdMyo7 in amoeba, are essential for filopodia...

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Detalles Bibliográficos
Autores principales: Arthur, Ashley L, Crawford, Amy, Houdusse, Anne, Titus, Margaret A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352590/
https://www.ncbi.nlm.nih.gov/pubmed/34042588
http://dx.doi.org/10.7554/eLife.68082