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In vivo analysis reveals that ATP-hydrolysis couples remodeling to SWI/SNF release from chromatin

ATP-dependent chromatin remodelers control the accessibility of genomic DNA through nucleosome mobilization. However, the dynamics of genome exploration by remodelers, and the role of ATP hydrolysis in this process remain unclear. We used live-cell imaging of Drosophila polytene nuclei to monitor Br...

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Detalles Bibliográficos
Autores principales: Tilly, Ben C, Chalkley, Gillian E, van der Knaap, Jan A, Moshkin, Yuri M, Kan, Tsung Wai, Dekkers, Dick HW, Demmers, Jeroen AA, Verrijzer, C Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352592/
https://www.ncbi.nlm.nih.gov/pubmed/34313222
http://dx.doi.org/10.7554/eLife.69424