Autoregulatory control of microtubule binding in doublecortin-like kinase 1

The microtubule-associated protein, doublecortin-like kinase 1 (DCLK1), is highly expressed in a range of cancers and is a prominent therapeutic target for kinase inhibitors. The physiological roles of DCLK1 kinase activity and how it is regulated remain elusive. Here, we analyze the role of mammali...

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Detalles Bibliográficos
Autores principales: Agulto, Regina L, Rogers, Melissa M, Tan, Tracy C, Ramkumar, Amrita, Downing, Ashlyn M, Bodin, Hannah, Castro, Julia, Nowakowski, Dan W, Ori-McKenney, Kassandra M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352597/
https://www.ncbi.nlm.nih.gov/pubmed/34310279
http://dx.doi.org/10.7554/eLife.60126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352597/
https://www.ncbi.nlm.nih.gov/pubmed/34310279
http://dx.doi.org/10.7554/eLife.60126

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