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Computational screening of 645 antiviral peptides against the receptor-binding domain of the spike protein in SARS-CoV-2
The receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein plays a vital role in binding and internalization through the alpha-helix (AH) of human angiotensin-converting enzyme 2 (hACE2). Thus, it is a potential target for designing and developing antiviral agents. Inhibition of RBD activity...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352665/ https://www.ncbi.nlm.nih.gov/pubmed/34403938 http://dx.doi.org/10.1016/j.compbiomed.2021.104759 |