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Computational screening of 645 antiviral peptides against the receptor-binding domain of the spike protein in SARS-CoV-2
The receptor-binding domain (RBD) of SARS-CoV-2 spike (S) protein plays a vital role in binding and internalization through the alpha-helix (AH) of human angiotensin-converting enzyme 2 (hACE2). Thus, it is a potential target for designing and developing antiviral agents. Inhibition of RBD activity...
Autores principales: | Sakib, Md Minhas Hossain, Nishat, Aktiya Anjum, Islam, Mohammad Tarequl, Raihan Uddin, Mohammad Abu, Iqbal, Md Shahriar, Bin Hossen, Farhan Fuad, Ahmed, Mohammad Imran, Bashir, Md Samiul, Hossain, Takbir, Tohura, Umma Sumia, Saif, Saiful Islam, Jui, Nabilah Rahman, Alam, Mosharaf, Islam, Md Aminul, Hasan, Md Mehadi, Sufian, Md Abu, Ali, Md Ackas, Islam, Rajib, Hossain, Mohammed Akhter, Halim, Mohammad A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352665/ https://www.ncbi.nlm.nih.gov/pubmed/34403938 http://dx.doi.org/10.1016/j.compbiomed.2021.104759 |
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