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Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure

Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated wit...

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Detalles Bibliográficos
Autores principales: Segala, Francesco Vladimiro, Sgalla, Giacomo, Salvati, Federica, Berardini, Ludovica, Negri, Marcantonio, Nardella, Elisabetta, Potenza, Annalisa, Murri, Rita, Fantoni, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352674/
https://www.ncbi.nlm.nih.gov/pubmed/34388415
http://dx.doi.org/10.1016/j.rmed.2021.106571
Descripción
Sumario:Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated with methylprednisolone 1mg/kg for showing clinical and radiological features suggestive of OP at least 20 days after symptom onset and despite standard treatment for COVID-19.