Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure

Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated wit...

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Autores principales: Segala, Francesco Vladimiro, Sgalla, Giacomo, Salvati, Federica, Berardini, Ludovica, Negri, Marcantonio, Nardella, Elisabetta, Potenza, Annalisa, Murri, Rita, Fantoni, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352674/
https://www.ncbi.nlm.nih.gov/pubmed/34388415
http://dx.doi.org/10.1016/j.rmed.2021.106571
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author Segala, Francesco Vladimiro
Sgalla, Giacomo
Salvati, Federica
Berardini, Ludovica
Negri, Marcantonio
Nardella, Elisabetta
Potenza, Annalisa
Murri, Rita
Fantoni, Massimo
author_facet Segala, Francesco Vladimiro
Sgalla, Giacomo
Salvati, Federica
Berardini, Ludovica
Negri, Marcantonio
Nardella, Elisabetta
Potenza, Annalisa
Murri, Rita
Fantoni, Massimo
author_sort Segala, Francesco Vladimiro
collection PubMed
description Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated with methylprednisolone 1mg/kg for showing clinical and radiological features suggestive of OP at least 20 days after symptom onset and despite standard treatment for COVID-19.
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spelling pubmed-83526742021-08-10 Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure Segala, Francesco Vladimiro Sgalla, Giacomo Salvati, Federica Berardini, Ludovica Negri, Marcantonio Nardella, Elisabetta Potenza, Annalisa Murri, Rita Fantoni, Massimo Respir Med Correspondence Since the beginning of COVID-19 pandemic, clinical, radiological and histopathological features consistent with viral-induced organizing pneumonia (OP) have been reported as hallmark characteristics of the disease. Here, we describe the case of ten patients with severe COVID-19 pneumonia treated with methylprednisolone 1mg/kg for showing clinical and radiological features suggestive of OP at least 20 days after symptom onset and despite standard treatment for COVID-19. Elsevier Ltd. 2021-10 2021-08-10 /pmc/articles/PMC8352674/ /pubmed/34388415 http://dx.doi.org/10.1016/j.rmed.2021.106571 Text en © 2021 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Correspondence
Segala, Francesco Vladimiro
Sgalla, Giacomo
Salvati, Federica
Berardini, Ludovica
Negri, Marcantonio
Nardella, Elisabetta
Potenza, Annalisa
Murri, Rita
Fantoni, Massimo
Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure
title Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure
title_full Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure
title_fullStr Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure
title_full_unstemmed Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure
title_short Adjunctive corticosteroid treatment for organizing pneumonia in COVID-19 patients with persistent respiratory failure
title_sort adjunctive corticosteroid treatment for organizing pneumonia in covid-19 patients with persistent respiratory failure
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352674/
https://www.ncbi.nlm.nih.gov/pubmed/34388415
http://dx.doi.org/10.1016/j.rmed.2021.106571
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