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State-dependent inhibition of BK channels by the opioid agonist loperamide
Large-conductance Ca(2+)-activated K(+) (BK) channels control a range of physiological functions, and their dysfunction is linked to human disease. We have found that the widely used drug loperamide (LOP) can inhibit activity of BK channels composed of either α-subunits (BKα channels) or α-subunits...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352719/ https://www.ncbi.nlm.nih.gov/pubmed/34357374 http://dx.doi.org/10.1085/jgp.202012834 |