Cardiovascular injuries and SARS-COV-2 infection: focus on elderly people

The novel coronavirus disease (COVID-19) has hit the healthcare system worldwide. The risk of severe infection and mortality increases with advancing age, especially in subjects with comorbidities such as cardiovascular disease, hypertension, diabetes, obesity and cancer. Moreover, cardiovascular co...

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Detalles Bibliográficos
Autores principales: Colombo, Claudia, Garatti, Laura, Ferrante, Giulia, Casadei, Francesca, Montalto, Claudio, Crimi, Gabriele, Cogliati, Chiara, Ammirati, Enrico, Savonitto, Stefano, Morici, Nuccia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352775/
https://www.ncbi.nlm.nih.gov/pubmed/34404990
http://dx.doi.org/10.11909/j.issn.1671-5411.2021.07.001
Descripción
Sumario:The novel coronavirus disease (COVID-19) has hit the healthcare system worldwide. The risk of severe infection and mortality increases with advancing age, especially in subjects with comorbidities such as cardiovascular disease, hypertension, diabetes, obesity and cancer. Moreover, cardiovascular complications such as myocardial injury, heart failure and thromboembolism are frequently observed in COVID-19 cases, and several biomarkers (troponin, NTproBNP and D-Dimer) have been identified as prognostic indicators of disease severity and worst outcome. Currently, there is no specific therapy against SARS-CoV-2, although many medications are under investigation. The aim of this review will be to explore the intertwined relationship between COVID-19 disease and the cardiovascular system, focusing on elderly population. The available supportive treatments along with the related concerns in elderly patients, due to their comorbidities and polypharmacotherapy, will be explored.

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