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Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults

BACKGROUND: Metabolic syndrome (MetS) is a pathophysiological change based on the abnormal metabolism of many substances. The study aims to investigate the performance of visceral adiposity index (VAI) and lipid accumulation product (LAP) of MetS in young adults. METHODS: 448 young adults aged betwe...

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Autores principales: Liu, Xiaoli, Ma, Chunpeng, Yin, Fuzai, Wang, Rui, Lu, Qiang, Lu, Na, Ma, Chunming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352792/
https://www.ncbi.nlm.nih.gov/pubmed/34385979
http://dx.doi.org/10.3389/fendo.2021.719416
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author Liu, Xiaoli
Ma, Chunpeng
Yin, Fuzai
Wang, Rui
Lu, Qiang
Lu, Na
Ma, Chunming
author_facet Liu, Xiaoli
Ma, Chunpeng
Yin, Fuzai
Wang, Rui
Lu, Qiang
Lu, Na
Ma, Chunming
author_sort Liu, Xiaoli
collection PubMed
description BACKGROUND: Metabolic syndrome (MetS) is a pathophysiological change based on the abnormal metabolism of many substances. The study aims to investigate the performance of visceral adiposity index (VAI) and lipid accumulation product (LAP) of MetS in young adults. METHODS: 448 young adults aged between 19 and 24 years old in Qinhuangdao had been included in this cross-sectional study. Receiver operating characteristic (ROC) curve analyses were used to assess the accuracy of these two obesity indicators for MetS. RESULTS: The prevalence of MetS was 2.0%. In male subjects, LAP had the highest area under the ROC curve (AUC) value (AUC = 0.963), followed by VAI (AUC = 0.937). In female subjects, LAP also had the highest AUC value (AUC = 0.931), followed by VAI (AUC = 0.861). No significant difference was found between the two obesity indicators (P > 0.05). CONCLUSION: The two obesity indicators were valuable for the screening of MetS in young adults, and LAP was the simpler of the two.
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spelling pubmed-83527922021-08-11 Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults Liu, Xiaoli Ma, Chunpeng Yin, Fuzai Wang, Rui Lu, Qiang Lu, Na Ma, Chunming Front Endocrinol (Lausanne) Endocrinology BACKGROUND: Metabolic syndrome (MetS) is a pathophysiological change based on the abnormal metabolism of many substances. The study aims to investigate the performance of visceral adiposity index (VAI) and lipid accumulation product (LAP) of MetS in young adults. METHODS: 448 young adults aged between 19 and 24 years old in Qinhuangdao had been included in this cross-sectional study. Receiver operating characteristic (ROC) curve analyses were used to assess the accuracy of these two obesity indicators for MetS. RESULTS: The prevalence of MetS was 2.0%. In male subjects, LAP had the highest area under the ROC curve (AUC) value (AUC = 0.963), followed by VAI (AUC = 0.937). In female subjects, LAP also had the highest AUC value (AUC = 0.931), followed by VAI (AUC = 0.861). No significant difference was found between the two obesity indicators (P > 0.05). CONCLUSION: The two obesity indicators were valuable for the screening of MetS in young adults, and LAP was the simpler of the two. Frontiers Media S.A. 2021-07-26 /pmc/articles/PMC8352792/ /pubmed/34385979 http://dx.doi.org/10.3389/fendo.2021.719416 Text en Copyright © 2021 Liu, Ma, Yin, Wang, Lu, Lu and Ma https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Liu, Xiaoli
Ma, Chunpeng
Yin, Fuzai
Wang, Rui
Lu, Qiang
Lu, Na
Ma, Chunming
Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults
title Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults
title_full Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults
title_fullStr Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults
title_full_unstemmed Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults
title_short Performance of Two Novel Obesity Indicators for the Management of Metabolic Syndrome in Young Adults
title_sort performance of two novel obesity indicators for the management of metabolic syndrome in young adults
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352792/
https://www.ncbi.nlm.nih.gov/pubmed/34385979
http://dx.doi.org/10.3389/fendo.2021.719416
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