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Tunable heat shock protein-mediated NK cell responses are orchestrated by STAT1 in Antigen Presenting Cells

The release of Heat Shock Proteins (HSPs) from aberrant cells can initiate immune responses following engagement of the HSPs with antigen presenting cells (APCs). This is an important mechanism for cancer immunosurveillance and can also be modeled by vaccination with HSPs through various routes, tar...

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Detalles Bibliográficos
Autores principales: Sedlacek, Abigail L., Kinner-Bibeau, Lauren B., Wang, Yifei, Mizes, Alicia P., Binder, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352880/
https://www.ncbi.nlm.nih.gov/pubmed/34373574
http://dx.doi.org/10.1038/s41598-021-95578-3