Benzalkonium chloride-induced myofibroblastic transdifferentiation of Tenon’s capsule fibroblasts is inhibited by coculture with corneal epithelial cells or by interleukin-10

Benzalkonium chloride (BAC) is used as a preservative in eyedrops but induces subconjunctival fibrosis that can result in failure of glaucoma surgery. Tenon’s capsule fibroblasts in subconjunctival tissue interact with the corneal epithelium through tear fluid. With the use of a coculture system, we...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamashiro, Chiemi, Tokuda, Kazuhiro, Kobayashi, Yuka, Higashijima, Fumiaki, Yoshimoto, Takuya, Ota, Manami, Ogata, Tadahiko, Ashimori, Atsushige, Kobayashi, Masaaki, Hatano, Makoto, Uchi, Sho-Hei, Wakuta, Makiko, Teranishi, Shinichiro, Kimura, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352883/
https://www.ncbi.nlm.nih.gov/pubmed/34373467
http://dx.doi.org/10.1038/s41598-021-94852-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352883/
https://www.ncbi.nlm.nih.gov/pubmed/34373467
http://dx.doi.org/10.1038/s41598-021-94852-8

Ejemplares similares