An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism

The implementation of applied engineering principles to create synthetic biological systems promises to revolutionize medicine, but application of fundamentally redesigned organisms has thus far not impacted practical drug development. Here we utilize an engineered microbial organism with a six-lett...

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Detalles Bibliográficos
Autores principales: Ptacin, Jerod L., Caffaro, Carolina E., Ma, Lina, San Jose Gall, Kristine M., Aerni, Hans R., Acuff, Nicole V., Herman, Rob W., Pavlova, Yelena, Pena, Michael J., Chen, David B., Koriazova, Lilia K., Shawver, Laura K., Joseph, Ingrid B., Milla, Marcos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352909/
https://www.ncbi.nlm.nih.gov/pubmed/34373459
http://dx.doi.org/10.1038/s41467-021-24987-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352909/
https://www.ncbi.nlm.nih.gov/pubmed/34373459
http://dx.doi.org/10.1038/s41467-021-24987-9

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