FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity

Classical dendritic cells (cDC) are professional antigen-presenting cells (APC) that regulate immunity and tolerance. Neutrophil-derived cells with properties of DCs (nAPC) are observed in human diseases and after culture of neutrophils with cytokines. Here we show that FcγR-mediated endocytosis of...

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Detalles Bibliográficos
Autores principales: Mysore, Vijayashree, Cullere, Xavier, Mears, Joseph, Rosetti, Florencia, Okubo, Koshu, Liew, Pei X., Zhang, Fan, Madera-Salcedo, Iris, Rosenbauer, Frank, Stone, Richard M., Aster, Jon C., von Andrian, Ulrich H., Lichtman, Andrew H., Raychaudhuri, Soumya, Mayadas, Tanya N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8352912/
https://www.ncbi.nlm.nih.gov/pubmed/34373452
http://dx.doi.org/10.1038/s41467-021-24591-x

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