The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection

During positive selection at the transition from CD4(+)CD8(+) double-positive (DP) to single-positive (SP) thymocyte, TCR signalling results in appropriate MHC restriction and signals for survival and progression. We show that the pioneer transcription factors Foxa1 and Foxa2 are required to regulat...

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Detalles Bibliográficos
Autores principales: Lau, Ching-In, Rowell, Jasmine, Yanez, Diana C., Solanki, Anisha, Ross, Susan, Ono, Masahiro, Crompton, Tessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353164/
https://www.ncbi.nlm.nih.gov/pubmed/34323272
http://dx.doi.org/10.1242/dev.199754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353164/
https://www.ncbi.nlm.nih.gov/pubmed/34323272
http://dx.doi.org/10.1242/dev.199754

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