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Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis

OBJECTIVES: The purpose of this systematic review of the literature is to investigate which of the epoxy-based cements and those based on Tricalciumsilicate (MTA, Bioceramic) have the best sealing capacity through the analysis of studies that have provided a survey model in vitro of bacteria leakage...

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Autores principales: Dioguardi, Mario, Alovisi, Mario, Sovereto, Diego, Troiano, Giuseppe, Malagnino, Giancarlo, Di Cosola, Michele, Cazzolla, Angela Pia, Laino, Luigi, Lo Muzio, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353296/
https://www.ncbi.nlm.nih.gov/pubmed/34401555
http://dx.doi.org/10.1016/j.heliyon.2021.e07494
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author Dioguardi, Mario
Alovisi, Mario
Sovereto, Diego
Troiano, Giuseppe
Malagnino, Giancarlo
Di Cosola, Michele
Cazzolla, Angela Pia
Laino, Luigi
Lo Muzio, Lorenzo
author_facet Dioguardi, Mario
Alovisi, Mario
Sovereto, Diego
Troiano, Giuseppe
Malagnino, Giancarlo
Di Cosola, Michele
Cazzolla, Angela Pia
Laino, Luigi
Lo Muzio, Lorenzo
author_sort Dioguardi, Mario
collection PubMed
description OBJECTIVES: The purpose of this systematic review of the literature is to investigate which of the epoxy-based cements and those based on Tricalciumsilicate (MTA, Bioceramic) have the best sealing capacity through the analysis of studies that have provided a survey model in vitro of bacteria leakage. SOURCE: The articles were identified using electronic databases such as PubMed, Scopus, the search was conducted between 8.12.2020 and 31.12.2020 and a last search was conducted on 2.12.2021. STUDY SELECTION: 678 records were identified and after removing the duplicates we obtain 481 records, with the first phase of screening and selection of records we reached 204 and with the application of the inclusion and exclusion criteria we selected 31 articles, only 9 studies made a direct comparison between the two endodontic cement categories and presented data that could be included in the metaanalysis. DATA: The meta-analysis of first outcome shows an odds ratio of 2.70 C.I.(Confidence Interval) [1.54, 4.73], the test for overall effect has a p value = 0.0005 with a heterogeneity index of I 2 of 9%; The second outcome meta-analysis shows an Odds Ratio of 1.50 C.I. (Confidence Interval) [0.92, 2.46] with a p value of 0.10 with an I 2 of 79%. CONCLUSION: the sealing ability is higher for epoxy resins than for tricalcium silicate-based cements, for observation periods longer than 90 days. CLINICAL RELEVANCE: The knowledge of the cement that determines the best sealing ability and resistance to microbial leakage, can be of help for the dentist who has to face clinical situations such as endodontic retreatments whose failure is determined by the persistence of bacteria in the endodontic canals.
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spelling pubmed-83532962021-08-15 Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis Dioguardi, Mario Alovisi, Mario Sovereto, Diego Troiano, Giuseppe Malagnino, Giancarlo Di Cosola, Michele Cazzolla, Angela Pia Laino, Luigi Lo Muzio, Lorenzo Heliyon Review Article OBJECTIVES: The purpose of this systematic review of the literature is to investigate which of the epoxy-based cements and those based on Tricalciumsilicate (MTA, Bioceramic) have the best sealing capacity through the analysis of studies that have provided a survey model in vitro of bacteria leakage. SOURCE: The articles were identified using electronic databases such as PubMed, Scopus, the search was conducted between 8.12.2020 and 31.12.2020 and a last search was conducted on 2.12.2021. STUDY SELECTION: 678 records were identified and after removing the duplicates we obtain 481 records, with the first phase of screening and selection of records we reached 204 and with the application of the inclusion and exclusion criteria we selected 31 articles, only 9 studies made a direct comparison between the two endodontic cement categories and presented data that could be included in the metaanalysis. DATA: The meta-analysis of first outcome shows an odds ratio of 2.70 C.I.(Confidence Interval) [1.54, 4.73], the test for overall effect has a p value = 0.0005 with a heterogeneity index of I 2 of 9%; The second outcome meta-analysis shows an Odds Ratio of 1.50 C.I. (Confidence Interval) [0.92, 2.46] with a p value of 0.10 with an I 2 of 79%. CONCLUSION: the sealing ability is higher for epoxy resins than for tricalcium silicate-based cements, for observation periods longer than 90 days. CLINICAL RELEVANCE: The knowledge of the cement that determines the best sealing ability and resistance to microbial leakage, can be of help for the dentist who has to face clinical situations such as endodontic retreatments whose failure is determined by the persistence of bacteria in the endodontic canals. Elsevier 2021-07-07 /pmc/articles/PMC8353296/ /pubmed/34401555 http://dx.doi.org/10.1016/j.heliyon.2021.e07494 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review Article
Dioguardi, Mario
Alovisi, Mario
Sovereto, Diego
Troiano, Giuseppe
Malagnino, Giancarlo
Di Cosola, Michele
Cazzolla, Angela Pia
Laino, Luigi
Lo Muzio, Lorenzo
Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis
title Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis
title_full Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis
title_fullStr Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis
title_full_unstemmed Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis
title_short Sealing ability and microbial leakage of root-end filling materials: MTA versus epoxy resin: A systematic review and meta-analysis
title_sort sealing ability and microbial leakage of root-end filling materials: mta versus epoxy resin: a systematic review and meta-analysis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353296/
https://www.ncbi.nlm.nih.gov/pubmed/34401555
http://dx.doi.org/10.1016/j.heliyon.2021.e07494
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