Novel Insights on MRGPRX2-Mediated Hypersensitivity to Neuromuscular Blocking Agents And Fluoroquinolones

Neuromuscular blocking agents (NMBAs) like atracurium and rocuronium as well as fluoroquinolones (FQs) cause mast cell-mediated anaphylaxis by activating Mas-related G protein-coupled receptor X2 (MRGPRX2), but many questions remain unanswered. Here, we address three of them, namely whether primary...

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Detalles Bibliográficos
Autores principales: Elst, Jessy, Maurer, Marcus, Sabato, Vito, Faber, Margaretha A., Bridts, Chris H., Mertens, Christel, Van Houdt, Michel, Van Gasse, Athina L., van der Poorten, Marie-Line M., De Puysseleyr, Leander P., Hagendorens, Margo M., Van Tendeloo, Viggo F., Lion, Eva, Campillo-Davo, Diana, Ebo, Didier G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353374/
https://www.ncbi.nlm.nih.gov/pubmed/34385999
http://dx.doi.org/10.3389/fimmu.2021.668962

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