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Protein phosphatase 1 regulatory subunit 18 suppresses the transcriptional activity of NFATc1 via regulation of c-fos

The transcription factor NFATc1 and its binding partner AP-1 (a complex containing c-fos and c-Jun) play a central role in osteoclast differentiation. NFATc1 and AP-1 promote the expression of target genes such as Acp5, Ctsk and also auto-regulate NFATc1 expression as well. We previously reported th...

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Detalles Bibliográficos
Autores principales:	Yasuda, Kazuma, Matsubara, Takuma, Shirakawa, Tomohiko, Kawamoto, Tatsuo, Kokabu, Shoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353383/ https://www.ncbi.nlm.nih.gov/pubmed/34401407 http://dx.doi.org/10.1016/j.bonr.2021.101114

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