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Structural characterization of the mitochondrial Ca(2+) uniporter provides insights into Ca(2+) uptake and regulation

The mitochondrial uniporter is a Ca(2+)-selective ion-conducting channel in the inner mitochondrial membrane that is involved in various cellular processes. The components of this uniporter, including the pore-forming membrane subunit MCU and the modulatory subunits MCUb, EMRE, MICU1, and MICU2, hav...

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Detalles Bibliográficos
Autores principales:	Wu, Wenping, Zheng, Jimin, Jia, Zongchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353469/ https://www.ncbi.nlm.nih.gov/pubmed/34401674 http://dx.doi.org/10.1016/j.isci.2021.102895

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