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Lineages of embryonic stem cells show non-Markovian state transitions

Pluripotent embryonic stem cells (ESCs) constitute the cell types of the adult vertebrate through a series of developmental state transitions. These states can be defined by expression levels of marker genes, such as Nanog and Sox2. In culture, ESCs reversibly transition between states. However, whe...

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Detalles Bibliográficos
Autores principales: Udomlumleart, Tee, Hu, Sofia, Garg, Salil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353490/
https://www.ncbi.nlm.nih.gov/pubmed/34401663
http://dx.doi.org/10.1016/j.isci.2021.102879