α2δ-1 switches the phenotype of synaptic AMPA receptors by physically disrupting heteromeric subunit assembly

Many neurological disorders show an increased prevalence of GluA2-lacking, Ca(2+)-permeable AMPA receptors (CP-AMPARs), which dramatically alters synaptic function. However, the molecular mechanism underlying this distinct synaptic plasticity remains enigmatic. Here, we show that nerve injury potent...

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Detalles Bibliográficos
Autores principales: Li, Lingyong, Chen, Shao-Rui, Zhou, Meng-Hua, Wang, Li, Li, De-Pei, Chen, Hong, Lee, Garam, Jayaraman, Vasanthi, Pan, Hui-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353586/
https://www.ncbi.nlm.nih.gov/pubmed/34289359
http://dx.doi.org/10.1016/j.celrep.2021.109396

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