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Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme

[Image: see text] Enantioselective protonation is conceptually one of the most attractive methods to generate an α-chiral center. However, enantioselective protonation presents major challenges, especially in water. Herein, we report a tandem Michael addition/enantioselective protonation reaction ca...

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Detalles Bibliográficos
Autores principales: Zhou, Zhi, Roelfes, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353628/
https://www.ncbi.nlm.nih.gov/pubmed/34386272
http://dx.doi.org/10.1021/acscatal.1c02298