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Ref-1 redox activity alters cancer cell metabolism in pancreatic cancer: exploiting this novel finding as a potential target

BACKGROUND: Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in therapeutic efficacy. Redox factor-1 (Ref-1), a redox signal...

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Detalles Bibliográficos
Autores principales:	Gampala, Silpa, Shah, Fenil, Lu, Xiaoyu, Moon, Hye-ran, Babb, Olivia, Umesh Ganesh, Nikkitha, Sandusky, George, Hulsey, Emily, Armstrong, Lee, Mosely, Amber L., Han, Bumsoo, Ivan, Mircea, Yeh, Jing-Ruey Joanna, Kelley, Mark R., Zhang, Chi, Fishel, Melissa L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353735/ https://www.ncbi.nlm.nih.gov/pubmed/34376225 http://dx.doi.org/10.1186/s13046-021-02046-x

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