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Characterization of an ETV6-NTRK3 rearrangement with unusual, but highly significant FISH signal pattern in a secretory carcinoma of the salivary gland: a case report

BACKGROUND: Fusions of neurotrophic tropomyosin receptor kinase genes NTRK1, NTRK2 and NTRK3 with various partner genes occur in both common and rare tumours and are of paramount predictive value due to the availability of very effective pan-Trk inhibitors like Larotrectinib and Entrectinib. Detecti...

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Detalles Bibliográficos
Autores principales: Wagner, Florian, Greim, Ralf, Krebs, Kathrin, Luebben, Finn, Dimmler, Arno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353763/
https://www.ncbi.nlm.nih.gov/pubmed/34372873
http://dx.doi.org/10.1186/s13000-021-01133-z