Adiponectin in psoriasis and its comorbidities: a review

Psoriasis is a chronic, immune-mediated inflammatory skin disease characterized by abnormal T cell activation and excessive proliferation of keratinocytes. In addition to skin manifestations, psoriasis has been associated with multiple metabolic comorbidities, such as obesity, insulin resistance, an...

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Autores principales: Ruiyang, Bai, Panayi, Adriana, Ruifang, Wu, Peng, Zhang, Siqi, Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353790/
https://www.ncbi.nlm.nih.gov/pubmed/34372872
http://dx.doi.org/10.1186/s12944-021-01510-z
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author Ruiyang, Bai
Panayi, Adriana
Ruifang, Wu
Peng, Zhang
Siqi, Fu
author_facet Ruiyang, Bai
Panayi, Adriana
Ruifang, Wu
Peng, Zhang
Siqi, Fu
author_sort Ruiyang, Bai
collection PubMed
description Psoriasis is a chronic, immune-mediated inflammatory skin disease characterized by abnormal T cell activation and excessive proliferation of keratinocytes. In addition to skin manifestations, psoriasis has been associated with multiple metabolic comorbidities, such as obesity, insulin resistance, and diabetes. An increasing amount of evidence has highlighted the core role of adipokines in adipose tissue and the immune system. This review focus on the role of adiponectin in the pathophysiology of psoriasis and its comorbidities, highlighting the future research avenues.
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spelling pubmed-83537902021-08-10 Adiponectin in psoriasis and its comorbidities: a review Ruiyang, Bai Panayi, Adriana Ruifang, Wu Peng, Zhang Siqi, Fu Lipids Health Dis Review Psoriasis is a chronic, immune-mediated inflammatory skin disease characterized by abnormal T cell activation and excessive proliferation of keratinocytes. In addition to skin manifestations, psoriasis has been associated with multiple metabolic comorbidities, such as obesity, insulin resistance, and diabetes. An increasing amount of evidence has highlighted the core role of adipokines in adipose tissue and the immune system. This review focus on the role of adiponectin in the pathophysiology of psoriasis and its comorbidities, highlighting the future research avenues. BioMed Central 2021-08-09 /pmc/articles/PMC8353790/ /pubmed/34372872 http://dx.doi.org/10.1186/s12944-021-01510-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Ruiyang, Bai
Panayi, Adriana
Ruifang, Wu
Peng, Zhang
Siqi, Fu
Adiponectin in psoriasis and its comorbidities: a review
title Adiponectin in psoriasis and its comorbidities: a review
title_full Adiponectin in psoriasis and its comorbidities: a review
title_fullStr Adiponectin in psoriasis and its comorbidities: a review
title_full_unstemmed Adiponectin in psoriasis and its comorbidities: a review
title_short Adiponectin in psoriasis and its comorbidities: a review
title_sort adiponectin in psoriasis and its comorbidities: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353790/
https://www.ncbi.nlm.nih.gov/pubmed/34372872
http://dx.doi.org/10.1186/s12944-021-01510-z
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AT ruifangwu adiponectininpsoriasisanditscomorbiditiesareview
AT pengzhang adiponectininpsoriasisanditscomorbiditiesareview
AT siqifu adiponectininpsoriasisanditscomorbiditiesareview

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