Ginsenoside Rb1 induces a pro-neurogenic microglial phenotype via PPARγ activation in male mice exposed to chronic mild stress

BACKGROUND: Anti-inflammatory approaches are emerging as a new strategy for the treatment of depressive disorders. Ginsenoside Rb1 (GRb1), a major component of Panax ginseng, can inhibit inflammatory cascade and alleviate depressive-like behaviors. Microglia can promote or inhibit adult hippocampal...

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Detalles Bibliográficos
Autores principales: Zhang, Lijuan, Tang, Minmin, Xie, Xiaofang, Zhao, Qiuying, Hu, Nan, He, Hui, Liu, Gangcai, Huang, Shiqi, Peng, Cheng, Xiao, Ying, You, Zili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353817/
https://www.ncbi.nlm.nih.gov/pubmed/34372875
http://dx.doi.org/10.1186/s12974-021-02185-0

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