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NMDAR modulators as rapid antidepressants: Converging and distinct signaling mechanisms
Dysregulation of the glutamatergic system underlies the pathophysiology of depression. Both negative and positive modulation of NMDARs exert rapid and sustained antidepressant effects by reversing the dysregulated glutamatergic system. Research in the past decades has identified key signaling pathwa...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353843/ https://www.ncbi.nlm.nih.gov/pubmed/34381955 http://dx.doi.org/10.15761/icm.1000173 |