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The CD226‐ERK1/2‐LAMP1 pathway is an important mechanism for Vγ9Vδ2 T cell cytotoxicity against chemotherapy‐resistant acute myeloid leukemia blasts and leukemia stem cells

Vγ9Vδ2 T cells are attractive effector cells for immunotherapy with potent cytotoxic activity against a variety of malignant cells. However, the effect of Vγ9Vδ2 T cells on chemotherapy‐resistant acute myeloid leukemia (AML) blasts, especially highly refractory leukemia stem cells (LSCs) is still un...

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Detalles Bibliográficos
Autores principales: Wu, Kangni, Wang, Li‐mengmeng, Liu, Meng, Xiu, Yanghui, Hu, Yongxian, Fu, Shan, Huang, He, Xu, Bing, Xiao, Haowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353902/
https://www.ncbi.nlm.nih.gov/pubmed/34107135
http://dx.doi.org/10.1111/cas.15014

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