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An AKT/PRMT5/SREBP1 axis in lung adenocarcinoma regulates de novo lipogenesis and tumor growth

Protein kinase B (AKT) hyperactivation and de novo lipogenesis are both common in tumor progression. Sterol regulatory element‐binding protein 1 (SREBP1) is the master regulator for tumor lipid metabolism, and protein arginine methyltransferase 5 (PRMT5) is an enzyme that can catalyze symmetric dime...

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Detalles Bibliográficos
Autores principales:	Liu, Liu, Yan, Hui, Ruan, Maomei, Yang, Hao, Wang, Lihua, Lei, Bei, Sun, Xiaoyan, Chang, Cheng, Huang, Gang, Xie, Wenhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353903/ https://www.ncbi.nlm.nih.gov/pubmed/34033176 http://dx.doi.org/10.1111/cas.14988

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